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Peritoneal Mesothelioma is a type of cancer that affects the peritoneum of the human abdominal cavity. Hence, this medical condition is also called as abdominal mesothelioma.

But before seeing more about peritoneal mesothelioma, let us first take a look at the classifications and functions of the peritoneum membrane.

Peritoneum is classified into visceral and parietal peritoneum. The visceral peritoneum envelops the abdominal organs and forms the periphery of the intestinal tract. On the other hand, parietal peritoneum covers the abdominal cavity. The purpose of these layers is to protect the internal organs and to secrete a lubricating fluid that eases the movement of internal organs in the abdominal cavity.

Causes of Peritoneal Mesothelioma

Even though not a definitive explanation, it is widely considered that asbestos is the main cause for peritoneal mesothelioma. According to medical experts, in two ways asbestos dust could reach the intestine lining one through involuntary ingestion during working long hours and days amid asbestos, and secondly, through the lungs while breathing and hence along the lymph nodes to the peritoneal cavity. Either way, it is injurious to the human body, and may invariably lead to this cancerous condition if exposed to for a longer period of time.

Symptoms of Peritoneal Mesothelioma

Peritoneal mesothelioma, like the other forms of mesothelioma, shows a very long latency period and it wont be until 20-30 years since the asbestos-exposure days before any typical symptoms becomes apparent. But by then it will be too late to check the disease or provide any constructive medication or treatment. Further, a delay in diagnosing the disease can happen due to the fact that most of the symptoms of mesothelioma is not-specific and may resemble that of some other common and less serious diseases. For example, the common mesothelioma symptoms include anemia, fever, weight loss, abdominal pain, and bowel obstruction, and it is highly likely that the doctor initially may consider other options than contemplating cancer. Therefore, the patient telling the doctor about any previous asbestos exposure in the first one-to-one interaction itself is very crucial, and that helps the doctor to think of a possible mesothelioma threat even before considering other possibilities.

Treatments

Once the disease has been diagnosed, the doctor recommends the treatments based on several factors such as the extent of the damage, age and medical history of the person and overall health. The traditional treatments for mesothelioma include surgery if the tumor has spread out and is beyond radiation-curable radiation therapy, external and internal radiation, and chemotherapy, which includes using a pill or needle to insert anti-carcinogen drugs into the body.

With the advancement in science and technology, newer treatment techniques have been introduced, and some of it is looking promising as well.

Intraoperative photodynamic therapy is one such newer method that uses special drugs and light to destroy cancer cells. This method is used to study the earlier phases of mesothelioma in the chest.

Further, Immunotherapy is a way of boosting the immunity of ones own body against the spread of cancer. Also, recently, researches have found that Gene Therapy is effective in correcting the faulty genes causing mesothelioma. But these two methods are still in the clinical trials and are yet to be implemented in hospitals.

Even though a wide range of treatments are available for mesothelioma, clinical experiences reveals that none of this alone is capable of checking the disease effectively. Therefore, it is a selected combination of some of these treatments called the “multimodality approach” that is commonly followed and the different modes of treatments to be used are decided by the doctor based on the given medical condition of the patient and his/her age.

Tail Piece Passive exposure to asbestos can also lead to mesothelioma. This happens when asbestos fibers reach the domestic setup through clothes dirties with asbestos dust. Therefore it is advisable that those handling asbestos may change their clothes before returning home or going to any public place.

Mesothelioma is a form of cancer. It caused by previous exposure to asbestos. An exposure of as little as one or two months can result in mesothelioma 30 or 40 years later. Simian virus 40 (SV40) may act as a cofactor in the development of mesothelioma. Malignant mesothelioma is the most serious of all asbestos-related diseases. The two major types of malignant mesothelioma are pleural mesothelioma, which concerns the mesothelium membrane that surrounds the lungs, and peritoneal mesothelioma which concerns the mesothelium layer that covers the organs in the abdominal cavity. The people most at risk from being carriers of this cancer are those have worked with asbestos over the past thirty to fifty years. Because of this, the disease is most common in men between the ages of sixty and seventy as this is the group that commonly worked with asbestos during those years. Because of the lack of protection and regulations in those days, these workers were constantly exposed to the dust and fibres from the asbestos, which caused the cells of the mesothelium to become abnormal. Many building materials used in both public and domestic premises prior to the banning of asbestos may contain asbestos. Those performing renovation works or diy activities may expose themselves to asbestos dust.

Mesothelium helps protect the organs by producing a special lubricating fluid that allows organs to move around. Mesothelioma is an extremely malignant and incurable cancer that infects the membrane that surrounds most of the internal organs. Symptoms of mesothelioma may not appear until 20 to 50 years after exposure to asbestos. Shortness of breath, cough, and pain in the chest due to an accumulation of fluid in the pleural space are often symptoms of pleural mesothelioma. Affecting the mesothelial cells that make up the mesothelium ? the outer lining that protects the body?s major organs such as the heart, stomach and lungs. Pleural mesothelioma represents 75% of mesothelioma cases – but it is far from the only type of this deadly cancer. Peritoneal mesothelioma affects the lining around the stomach and intestines, and is just as dangerous and deadly. Treatment of MM using conventional therapies has not proved successful and patients have a median survival time of 6 – 12 months after presentation. The clinical behaviour of the malignancy is affected by several factors including the continuous mesothelial surface of the pleural cavity

Mesothelioma Cancer Treatment and Prevention Tips

1. Health-care workers who specialize in part control are employing state-of-the art techniques to successfully fight pain.

2. During the initial stages of mesothelioma, pain can be relieved with over-the-counter analgesics, such as aspirin, Tylenol or ibuprofen (Advil, Motrin).

3. Drug therapy is the primary method for treating mesothelioma pain.

4. Non-Opoids are pain-relieving medicines such as acetaminophen (Tylenol) and NSAIDs, such as ibuprofin, which can be purchases over-the-counter and taken orally.

5. Opoids are the strongest medicines available to treat pain. Opoids, such as codeine, morphine, oxcodone, fentany, and hydromorphone, are very effective in relieving mesothelioma pain.

6. Adjuvant analgesics are medicines intended for purposes other than pain relief. A number of these are used to alleviate pain associated with mesothelioma, such as antidepressants, anticonvulsants, and steroids.

7. Emotional Support to Help Relieve Pain.As with all aspects of mesothelioma, emotional support from family or professional counseling can play a key role in pain management

8. For patients with localized disease, and who can tolerate a radical surgery, radiation is often given post-operatively as a consolidative treatment.

9. Chrysotile has been used more frequently, hence many mesotheliomas are caused by chrysotile.

10. Removal is taking place in schools and other public buildings throughout the U.S. The hope is that these measures will greatly reduce the occurrence of this cancer.

Mesothelioma, or the cancer of mesothelium, is a fatal tumor that affects pleura, peritoneum, and pericardium – linings around lungs, abdomen, and heart respectively. It is a fatal disease caused by exposure to asbestos, a naturally occurring mineral.

Mesothelioma cancer be benign, i.e. it can be non-cancerous and non-spreading or it can be malignant i.e. cancerous and spread to other parts of the body leading to death. Its primary cause is prolonged exposure to asbestos and it has a latency period of about 30 to 50 years.

Types of Mesothelioma

Mesothelioma can be classified into three types depending on the area of body affected by it. There are 3 common types of mesothelioma:

1. Pleural Mesothelioma

2. Peritoneal Mesothelioma

3. Pericardial Mesothelioma

Pleural Mesothelioma

The most common form of mesothelioma, Pleural Mesothelioma (cancer of pleura) is a tumor of the protective lining around the lungs. It can be either benign or malignant.

The pleura is a sac-like membrane made of two layers between which the pleural fluid is released. This fluid in turn acts like a lubricating agent and helps the lungs to function smoothly during breathing.

Symptoms

Common symptoms of Pleural Mesothelioma are:

* Shortness of breath

* Chest pain

* Back pain

* Pain in the rib cage

Other symptoms of Pleural Mesothelioma, for both benign and cancerous forms, include:

* Fluid build-up in the lung lining

* Hoarseness

* Coughing up blood

* Swelling of the face and arms

* Muscle weakness

* Paralysis

* Sensory loss

Peritoneal Mesothelioma

Another common form of mesothelioma is peritoneal mesothelioma or cancer of the peritoneum that causes tumor in the abdominal lining. Like pleural it can be benign or malignant.

The peritoneum is the membrane that covers most of the organs in the abdominal cavity and also includes:

* Tunica Vaginalis Testis (mesothelial tissue lining the male internal reproductive organs)

* Tunica Serosa Uteri (mesothelial tissue lining the female reproductive organs)

Symptoms

The fluid released in the peritoneum helps in the smooth functioning of these organs. When the peritoneum is affected, some common symptoms experienced are:

* Stomach pain

* Weight loss

* Nausea

* Vomiting

* Hernia

* Bowel obstruction

* Fluid in the abdominal cavity

If the cancer spreads beyond the abdominal cavity, additional symptoms can be found, such as:

* Anemia

* Blood clotting abnormalities

* Trouble swallowing

* Swelling of neck, face or arms

Pericardial Mesothelioma
Pericardial Mesothelioma or the cancer of pericardium is a tumor of the protective sac-like lining around the heart.

Pericardium protects the heart by:

* Smoothening its motion against surrounding organs

* Limiting its motion so that it stays in the chest cavity

* Preventing it from over-expansion during excess influx of blood

Symptoms

When pericardium’s function is affected by mesothelioma, the following symptoms may occur:

* Chest pain

* Shortness of breath

* Fluid accumulation in the lining

If the mesothelioma cancer spreads to other organs of the body, it can affect their normal functioning and cause painful symptoms. Thus, it is important that mesothelioma cancer is diagnosed on time and proper treatment is given to save the patient’s life.